Stinky farts are healthy

A study has found that gas relaxes the blood vessels to prevent hypertension in mice.

A smelly rotten-egg gas in farts controls blood pressure in mice, a new study finds.

The unpleasant aroma of the gas, called hydrogen sulfide (H2S), can be a little too familiar, as it is expelled by bacteria living in the human colon and eventually makes its way, well, out.

The new research found that cells lining mice’s blood vessels naturally make the gas and this action can help keep the rodents’ blood pressure low by relaxing the blood vessels to prevent hypertension (high blood pressure). This gas is “no doubt” produced in cells lining human blood vessels too, the researchers said.

Hydrogen sulfide is the most recently discovered member of a family of gasotransmitters, small molecules inside our bodies with important physiological functions.

This study is the first to reveal that the CSE enzyme that triggers hydrogen sulfide is activated itself in the same way as other enzymes when they trigger their respective gasotransmitter, such as a nitric oxide-forming enzyme that also regulates blood pressure, Dr. Snyder said.

Because gasotransmitters are common in mammals all over the evolutionary tree, these findings on the importance of hydrogen sulfide are thought to have broad applications to human diseases, such as diabetes and neurodegenerative diseases.

— Full Report

Horny Goat Weed

A more natural solution to impotence.

LONDON (Reuters) - A Chinese herbal remedy called horny goat weed is a promising alternative to Viagra for impotent men, Italian researchers said on Monday.

The herb has long held a reputation as a natural aphrodisiac. The lab experiments, which did not look at whether the plant actually increases desire, could lead to new drugs to help men get erections, said Mario Dell'Agli, a researcher at the University of Milan, who led the study.

"This could be the natural Viagra," he said in a telephone interview. "The novelty is that we have synthesized a new molecule that one day may be able to replace Viagra."

Erectile dysfunction is a common condition worldwide, and drugs like Pfizer Inc's Viagra, Eli Lilly and Co's Cialis or tadalafil, and Bayer AG's Levitra or vardenafil, work by increasing blood flow to the genitals.

But the medicines, which inhibit an enzyme called phosphodiesterase type 5 that restricts blood flow around the body, including to the penis, can have side effects ranging from headaches, upset stomach and visual problems including blindness.

The Italian team looked for alternatives by studying a number of plants reputed to boost sexual performance.

After homing in on horny goat weed, the researchers modified a compound in the plant called icariin and found it blocked the erection-inhibiting enzyme as well as Viagra did.

— Full Story